Sanwei Science Pilot 50 Preparation Liquid Chromatography is a typical preparation chromatography system. Although it has a width of less than 30 centimeters and a small and exquisite volume, it has a large preparation capacity. The pilot series preparation liquid chromatography and high-pressure preparation liquid chromatography adopt modular design, with powerful functions and simple system operation, allowing gradient elution using up to 4 different solvents. Two wavelengths are simultaneously detected online, making it easy to store and call methods, and complete fraction collection work on the same platform. It supports the system connection of stainless steel chromatography columns and high-pressure glass chromatography columns, and is widely used for the separation, purification, and preparation of target active ingredients such as Chinese herbal medicine, natural products, organic synthesis products, and protein biopolymers. From laboratory research to industrial production, it can meet their requirements.

Technical characteristics of Pilot50 preparation liquid chromatography system:

• Can quickly complete the purification and preparation of small molecule and large molecule active ingredient compounds

• Highly flexible modular configuration, integrated fraction collection, making the scientific research process more intuitive

• Cam curve compensation technology effectively controls flow pulsation and ensures low baseline noise

• Multi point flow correction curve ensures flow accuracy and system repeatability across the entire flow range

• The pump head has an automatic cleaning function to avoid buffer residue and crystal precipitation

• Simultaneous detection of dual wavelengths within the range of 190-800nm for reliable online analysis of main components, by-products, and impurities

• Convenient replacement of lamps and circulation pools, intelligent switching of deuterium and tungsten lamps to ensure maximum operating time

• High sensitivity online detection, system supports optional UV, ELSD, RI and other detectors

• 316L stainless steel PEEK、 Pure titanium, Hastelloy alloy, and a variety of flow path materials to choose from

• Fully automatic fraction collector with multiple collection modes and configurable collection tubes of various specifications

• Project management adopts database mode to manage data, and the instrument methods, spectral data, and analysis methods associated with the project are all stored under the project

• Strictly manage permissions, electronic records, electronic signatures, audit tracking functions, execute user registration and multiple permission settings

• The system control software fully complies with CFDA GxP and FDA 21CFR Part 11 regulatory requirements

• The system can be adapted and connected to any brand of chromatography column or SPE solid-phase extraction column

Automatic Collector Features:
• Unique motion principle, combining linear and rotational motion, can quickly reach any collection position;
Multiple collection modes are available, including volume, time, threshold, and slope combinations, to meet various collection needs
Establish regular mode, sequential collection, and cyclic collection;
Small pipeline design to reduce inaccurate collection caused by sample diffusion in the flow cell;
• Setting software delay volume for accurate collection and purer product;
Adopting high-precision bottle cutting technology, the waste liquid channel is independent, and there is no dripping during the bottle switching process;
Divided into two collection methods, dynamic and automatic, with simple and convenient operation;
The supporting software can collect multiple wavelength signals in real time, and the collected signals can be selected arbitrarily;
Real time display of device status, connection, and collection bottle location, with intuitive collection and clear location;
• Compatible with multiple collection containers, allowing up to bottles to be collected: 120 13-15mm test tubes;
• It has a self identification function for collection containers, which can prevent misplacement when using different types of collection containers;
Maximize space utilization, with devices occupying minimal space and easy to use.

Pilot50 Preparation Liquid Chromatography Technical Parameters: